Foldamer Tertiary Structure through Sequence-Guided Protein Backbone Alteration
نویسندگان
چکیده
منابع مشابه
InterPreTS: protein Interaction Prediction through Tertiary Structure
SUMMARY InterPreTS (Interaction Prediction through Tertiary Structure) is a web-based version of our method for predicting protein-protein interactions (Aloy and Russell, 2002, PROC: Natl Acad. Sci. USA, 99, 5896-5901). Given a pair of query sequences, we first search for homologues in a database of interacting domains (DBID) of known three-dimensional complex structures. Pairs of sequences hom...
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Peroxidase enzymes are vastly applicable in industry and diagnosiss. Recently, we introduced a new kind of peroxidase gene from Lepidium draba (LDP). According to protein multiple sequence alignment results, LDP had 93% similarity and 88.96% identity with horseradish peroxidase C1A (HRP C1A). In the current study we employed in silico tools to determine, to which group of peroxidase enzymes LDP...
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Four levels in protein structural organization are commonly identified. Primary structure is a sequence of amino acids. Secondary structure is represented by regular local conformations of polypeptide chain, such as α-helix or β-strand. The combinations of two secondary structure elements are also sometimes referred to as secondary (or supersecondary) structure. The example is a β-hairpin forme...
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ژورنال
عنوان ژورنال: Accounts of Chemical Research
سال: 2018
ISSN: 0001-4842,1520-4898
DOI: 10.1021/acs.accounts.8b00048