FtsN—Trigger for Septation
نویسندگان
چکیده
منابع مشابه
Fission yeast septation
In animal cells cytokinesis relies on the contraction of an actomyosin ring that pulls the plasma membrane to create a cleavage furrow, whose ingression finally divides the mother cell into two daughter cells. Fungal cells are surrounded by a tough and flexible structure called cell wall, which is considered to be the functional equivalent of the extracellular matrix in animal cells. Therefore,...
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Like DNA replication or chromosome segregation, cytokinesis is a once-and-only-once event in the life of a cell. What controls where, when and how a cell divides? The fission yeast Schizosaccharomyces pombe has recently become a focus for genetic studies of eukaryotic cytokinesis, and this work has revealed, among other things, a novel signal transduction pathway controlling septation [1–3]. Wh...
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BACKGROUND Schizosaccharomyces pombe pik1 encodes a phosphatidylinositol 4-kinase, reported to bind Cdc4, but not Cdc4(G107S). PRINCIPAL FINDINGS Gene deletion revealed that pik1 is essential. In cells with pik1 deleted, ectopic expression of a loss-of-function allele, created by fusion to a temperature-sensitive dihydrofolate reductase, allowed normal cell proliferation at 25 degrees C. At 3...
متن کاملThe mitotic exit and septation initiation networks.
Co-ordination of anaphase onset with cytokinesis, inactivation of mitotic CDK (cyclin-dependent kinase) activity, and spindle disassembly is important to assure faithful transmission of the genome from mother to daughter cells and maintenance of ploidy. Our knowledge of how this is achieved is most complete in the yeasts Schizosaccharomyces pombe and Saccharomyces cerevisiae. In both organisms,...
متن کاملsonic hedgehog is required in pulmonary endoderm for atrial septation.
The genesis of the septal structures of the mammalian heart is central to understanding the ontogeny of congenital heart disease and the evolution of cardiac organogenesis. We found that Hedgehog (Hh) signaling marked a subset of cardiac progenitors specific to the atrial septum and the pulmonary trunk in the mouse. Using genetic inducible fate mapping with Gli1(CreERT2), we marked Hh-receiving...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2009
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.01100-09