Functional joint regeneration is achieved using reintegration mechanism in Xenopus laevis

Functional joint regeneration is achieved using reintegration mechanism in Xenopus laevis

A functional joint requires integration of multiple tissues: the apposing skeletal elements should form an interlocking structure, and muscles should insert into skeletal tissues via tendons across the joint. Whereas newts can regenerate functional joints after amputation, Xenopus laevis regenerates a cartilaginous rod without joints, a "spike." Previously we reported that the reintegration mec...

Forelimb spike regeneration in Xenopus laevis: Testing for adaptiveness.

Experiments were designed to test adaptability of forelimb spike regenerates in Xenopus laevis froglets. The results show that when amputation is at the radius/ulna level, regeneration occurs in 100% of the cases and a single spike of cartilage is the result. The spike regenerates originating from radius/ulna level amputations can be used for feeding and froglet growth is only minimally comprom...

A Level Set Approach to Simulating Xenopus laevis Tail Regeneration

A framework for predictively linking cell-level signaling with larger scale patterning in regeneration and growth has yet to be created within the field of regenerative biology. If this could be achieved, regeneration (controlled cell growth), cancer (uncontrolled cell growth), and birth defects (mispatterning of cell growth) could be more easily understood and manipulated. This paper looks to ...

Cellular mechanism underlying neural convergent extension in Xenopus laevis embryos.

Convergent extension, the simultaneous narrowing and lengthening of a tissue, plays a major role in shaping and patterning the neural ectoderm in vertebrate embryos. In this paper, we characterize the cellular mechanism underlying convergent extension of the neural ectoderm in the Xenopus laevis late gastrula and neurula embryo. Neural ectoderm in X. laevis consists of two components, a superfi...

ترتیب اعصای جانبی در دم لارو of Xenopus laevis