Functional Mechanism of Channelrhodopsins
نویسندگان
چکیده
منابع مشابه
From channelrhodopsins to optogenetics
» . . .the photoreceptor and ion channel were intimately linked, forming a single protein. . . « We did not expect that research on the molecular mechanism of algal phototaxis or archaeal light-driven ion transport might interest readers of a medical journal when we conceived and performed our experiments a decade ago. On the other hand, it did not escape our attention that channelrhodopsin is ...
متن کاملFrom channelrhodopsins to optogenetics†
» . . .the photoreceptor and ion channel were intimately linked, forming a single protein. . . « We did not expect that research on the molecular mechanism of algal phototaxis or archaeal light-driven ion transport might interest readers of a medical journal when we conceived and performed our experiments a decade ago. On the other hand, it did not escape our attention that channelrhodopsin is ...
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in fact, this study focused on the following questions: 1. is there any difference between the effect of functional/notional approach and the structural approaches to language teaching on the proficiency test of efl learners? 2. can a rather innovative language test referred to as "functional test" ge devised so so to measure the proficiency test of efl learners, and thus be as much reliable an...
15 صفحه اولIntramolecular proton transfer in channelrhodopsins.
Channelrhodopsins serve as photoreceptors that control the motility behavior of green flagellate algae and act as light-gated ion channels when heterologously expressed in animal cells. Here, we report direct measurements of proton transfer from the retinylidene Schiff base in several channelrhodopsin variants expressed in HEK293 cells. A fast outward-directed current precedes the passive chann...
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Channelrhodopsin-2 is a light-gated ion channel and a major tool of optogenetics. It is used to control neuronal activity via blue light. Here we describe the construction of color-tuned high efficiency channelrhodopsins (ChRs), based on chimeras of Chlamydomonas channelrhodopsin-1 and Volvox channelrhodopsin-1. These variants show superb expression and plasma membrane integration, resulting in...
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ژورنال
عنوان ژورنال: Nippon Laser Igakkaishi
سال: 2016
ISSN: 0288-6200,1881-1639
DOI: 10.2530/jslsm.jslsm-36_0039