Functions of Class V Myosins in Neurons
نویسندگان
چکیده
منابع مشابه
Functions of class V myosins in neurons.
This minireview focuses on recent studies implicating class V myosins in organelle and macromolecule transport within neurons. These studies reveal that class V myosins play important roles in a wide range of fundamental processes occurring within neurons, including the transport into dendritic spines of organelles that support synaptic plasticity, the establishment of neuronal shape, the speci...
متن کاملProcessivity of chimeric class V myosins.
Unconventional myosin V takes many 36-nm steps along an actin filament before it dissociates, thus ensuring its ability to move cargo intracellularly over long distances. In the present study we assessed the structural features that affect processive run length by analyzing the properties of chimeras of mouse myosin V and a non-processive class V myosin from yeast (Myo4p) (Reck-Peterson, S. L.,...
متن کاملDissecting the functions of class XI myosins in moss and Arabidopsis.
Myosin XI strides along actin tracks at rates of up to 7 mm/s, making it the fastest known processive molecular motor (Tominaga et al., 2003). Class XI myosins are unique to plants and have been implicated in plant growth, intracellular transport, and root hair elongation (Prokhnevsky et al., 2008). Arabidopsis thaliana contains 13 class XImyosins, 6 of which are expressed predominantly in male...
متن کاملMyosins: matching functions with motors.
It is an exciting time to be studying myosins and their roles in the function of cells and organisms. Past efforts aimed at finding new members of this family have now given way to a focus on identifying individual functions for each motor protein. These actin-based motors are now known to be intimately involved in the following processes: neurosensory function; vesicle trafficking; determinant...
متن کاملClass I myosins have overlapping and specialized functions in left-right asymmetric development in Drosophila.
The class I myosin genes are conserved in diverse organisms, and their gene products are involved in actin dynamics, endocytosis, and signal transduction. Drosophila melanogaster has three class I myosin genes, Myosin 31DF (Myo31DF), Myosin 61F (Myo61F), and Myosin 95E (Myo95E). Myo31DF, Myo61F, and Myo95E belong to the Myosin ID, Myosin IC, and Myosin IB families, respectively. Previous loss-o...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2013
ISSN: 0021-9258
DOI: 10.1074/jbc.r113.514497