Gating and selectivity mechanisms for the lysosomal K+ channel TMEM175
نویسندگان
چکیده
منابع مشابه
TMEM175 Is an Organelle K+ Channel Regulating Lysosomal Function
Potassium is the most abundant ion to face both plasma and organelle membranes. Extensive research over the past seven decades has characterized how K(+) permeates the plasma membrane to control fundamental processes such as secretion, neuronal communication, and heartbeat. However, how K(+) permeates organelles such as lysosomes and endosomes is unknown. Here, we directly recorded organelle K(...
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ژورنال
عنوان ژورنال: eLife
سال: 2020
ISSN: 2050-084X
DOI: 10.7554/elife.53430