Gene expression in triple-negative breast cancer in relation to survival
نویسندگان
چکیده
منابع مشابه
Gene Expression Changes in Pomegranate Peel Extract-Treated Triple-Negative Breast Cancer Cells
Background: Triple-negative breast cancer (TNBC) is treated with highly aggressive non-targeted chemotherapies. Safer and more effective therapeutic approaches than those currently in use are needed. Natural pomegranate peel extract (PPE) has recently been found to inhibit breast cancer progression; however, its mechanisms of action remain unclear. We hypothesized that transcriptional chan...
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Background: Previous data have shown the tumorigenicity roles of HDAC8 in breast cancer. More recently, the oncogenic effects of this molecule have been revealed in TNBC. The present study aimed to determine the diagnostic value of HDAC8 for the differentiation of TNBC from nTNBC tumors. Methods: A total of 50 cancerous and normal adjacent tumor specimens were obtained, and the clinical and pat...
متن کاملtriple-negative breast cancer survival in iranian patients.
this study focused on triple-negative breast cancer (tnbc) that is characterized by the lack of expression of estrogen receptor (er), progesterone receptor (pr), and human epidermal growth factor receptor 2 (her-2). the primary goal of this study was to describe the relation between triple-negative receptor status and survival. this is the first study about triple-negative breast cancer in our ...
متن کاملTriple-negative breast cancer survival in Iranian patients.
This study focused on triple-negative breast cancer (TNBC) that is characterized by the lack of expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2). The primary goal of this study was to describe the relation between triple-negative receptor status and survival. This is the first study about triple-negative breast cancer in our ...
متن کاملCancer-testis antigen expression in triple-negative breast cancer.
BACKGROUND cancer-testis (CT) antigens, frequently expressed in human germline cells but not in somatic tissues, may become aberrantly reexpressed in different cancer types. The aim of this study was to investigate the expression of CT antigens in breast cancer. PATIENTS AND METHODS a total of 100 selected invasive breast cancers, including 50 estrogen receptor (ER) positive/HER2 negative and...
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ژورنال
عنوان ژورنال: Breast Cancer Research and Treatment
سال: 2018
ISSN: 0167-6806,1573-7217
DOI: 10.1007/s10549-018-4816-9