Gene expression profiling analysis of hepatocellular carcinoma
نویسندگان
چکیده
منابع مشابه
Gene expression profiling analysis of hepatocellular carcinoma
BACKGROUND Primary hepatocellular carcinoma (HCC) is one of the most common malignancies in the world. However, the molecular pathogenesis of HCC is not well-understood, and the prognosis for patients with HCC remains very poor. METHODS To disclose detailed genetic mechanisms in hepatocellular carcinoma (HCC) with a view toward development of novel therapeutic targets, we analyzed expression ...
متن کاملRetraction Note: Gene expression profiling analysis of hepatocellular carcinoma
Retraction The Publisher and Editor regretfully retract this article [1] because the peer-review process was inappropriately influenced and compromised. As a result, the scientific integrity of the article cannot be guaranteed. A systematic and detailed investigation suggests that a third party was involved in supplying fabricated details of potential peer reviewers for a large number of manusc...
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Previous papers reported the effectiveness in classification of cancers with their gene expression portraits [1, 2, 3]. Golub et al. [3] selected 50 genes of high predictive value to differentiate 2 types of leukemia by ‘weighted voting algorithm’. However it remains to be known whether we can apply this type of specific algorithms to classify different types of cancer. We, therefore, attempted...
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PURPOSE Hepatocellular carcinoma (HCC), a common cancer worldwide, has a dismal outcome partly due to the poor identification of early-stage HCC. Currently, one third of HCC patients present with low serum alpha-fetoprotein (AFP) levels, the only clinically available diagnostic marker for HCC. The aim of this study was to identify new diagnostic molecular markers for HCC, especially for individ...
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Microarray techniques using cDNA array and comparative genomic hybridization (CGH) have been developed for several discovery applications. They are frequently applied for the prediction and diagnosis of cancer in recent years. Many studies have shown that integrating genomic data from different sources may increase the reliability of gene expression analysis results in understanding cancer prog...
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ژورنال
عنوان ژورنال: European Journal of Medical Research
سال: 2013
ISSN: 2047-783X
DOI: 10.1186/2047-783x-18-44