Genetic Diversity of MSP1 Block 2 ofPlasmodium vivaxIsolates from Manaus (Central Brazilian Amazon)

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Genetic Diversity of MSP1 Block 2 of Plasmodium vivax Isolates from Manaus (Central Brazilian Amazon)

The diversity of MSP1 in both Plasmodium falciparum and P. vivax is presumed be associated to parasite immune evasion. In this study, we assessed genetic diversity of the most variable domain of vaccine candidate N-terminal PvMSP1 (Block 2) in field isolates of Manaus. Forty-seven blood samples the polymorphism of PvMSP1 Block 2 generates four fragment sizes. In twenty-eight of them, sequencing...

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ژورنال

عنوان ژورنال: Journal of Immunology Research

سال: 2014

ISSN: 2314-8861,2314-7156

DOI: 10.1155/2014/671050