Genetic diversity of Staphylococcus aureus isolated from different clinical samples at Modibbo Adama University Teaching Hospital, Yola using RAPD-PCR

Staphylococcus aureus (S. aureus) is a Gram-positive bacterium that causes wide range of variable illnesses and can be either transmitted from one place to another through contact with patients or airborne. Because the increased diversity S. globally, particularly those are clinical significance, rapid epidemiology bacteria, there need explore current pattern in our local settings. To achieve this target, for genetic method fast, easy, cost- effective able genetically differentiate between microbes within given species. Hence, study utilized simplicity RAPD-PCR as fingerprinting tool determining isolated samples setting. Eighteen isolates were RAPD-typed using single primer analyzed NTSYSpc software. Of 12 RAPD profiles identified, two major groups clusters deduced dendrogram. More so, ten subtypes identified amongst which three indistinguishable based on Jaccard's coefficient similarity. The findings reveals most closely related suggesting may have emerged clones. Equally, result depicts high-resolution power elucidating aureus. Therefore, simple molecular technique could employed routine studies settings country whole.