Genetic predisposition to sarcoidosis: another brick in the wall: Table 1–
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Genetic predisposition to sarcoidosis: another brick in the wall.
T he belief that a genetic susceptibility to the development of sarcoidosis exists is supported by several lines of evidence: 1) monozygotic twins are more often concordant for the disease than dizygotic twins; 2) sarcoidosis patients are more likely than healthy subjects to report a sibling or parent affected with the disease; 3) prevalence, incidence and severity of sarcoidosis vary widely am...
متن کاملAnother brick in the wall.
Sao Paulo Med J/Rev Paul Med 2002; 120(2):35. The history of lung cancer spans many years, and over recent decades excision of tumors has been considered as the only effective treatment. In 1933 Graham performed the first successful pneumonectomy due to lung cancer. In 1937 Ochsner and DeBakey first concluded that smoking is a cause of lung cancer. This important observation was confirmed by Do...
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Nearly all bacteria contain a peptidoglycan cell wall. The peptidoglycan precursor molecule is LipidII, containing the basic peptidoglycan building block attached to a lipid. Although the suitability of LipidII as an antibacterial target has long been recognized, progress on elucidating the role(s) of LipidII in bacterial cell biology has been slow. The focus of this review is on exciting new d...
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Sarcoidosis is a systemic noncaseating granulomatous disease that can affect any organ, while lungs, lymph nodes, and skin seem to be the most commonly affected organs (1,2). We read with interest the recent paper, entitled “Unusual manifestation of cutaneous sarcoidosis: a case report of morpheaform sarcoidosis”, published in the Acta Medica Iranica (3). The authors presented a case of cutaneo...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2013
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.00159912