Genetically engineered mouse models of melanoma
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چکیده
منابع مشابه
Genetically Engineered Mouse Models of Pituitary Tumors
Animal models constitute valuable tools for investigating the pathogenesis of cancer as well as for preclinical testing of novel therapeutics approaches. However, the pathogenic mechanisms of pituitary-tumor formation remain poorly understood, particularly in sporadic adenomas, thus, making it a challenge to model pituitary tumors in mice. Nevertheless, genetically engineered mouse models (GEMM...
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Despite major improvement in treatment of early stage localised prostate cancer, the distinction between indolent tumors and those that will become aggressive, as well as the lack of efficient therapies of advanced prostate cancer, remain major health problems. Genetically engineered mice (GEM) have been extensively used to investigate the molecular and cellular mechanisms underlying prostate t...
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ژورنال
عنوان ژورنال: Cancer
سال: 2017
ISSN: 0008-543X
DOI: 10.1002/cncr.30684