Germ cell‐specific expression of Cre recombinase using the VASA promoter in the pig

Mouse opsin promoter-directed Cre recombinase expression in transgenic mice.

PURPOSE Gene inactivation with homologous recombination in mice is a widely used tool to study gene function. However, many proteins play essential roles in a number of tissues and germline gene inactivation often results in embryonic lethality. To overcome this limitation and to dissect the functions of essential genes beyond embryonic development, we generated mouse rod opsin promoter-control...

Megakaryocyte-restricted expression of the Cre recombinase.

doi:10.1160/TH11-03-0150 Thromb Haemost 2011; 106: 554 Dear Sirs, In the recently published work from Adam Nowakowski et al. “Megakaryocyte gene targeting mediated by restricted expression of recombinase Cre” (Thromb Haemost 2011; 105.1) the authors present a transgenic mouse strain that allows Cre expression under the control of the alphaIIb promoter (1). Nowakowski et al. (1) suggest that thi...

the effect of using critical discourse analytical tools on the improvement of the learners level of critical thinking in reading comprehension

?it is of utmost priority for an experienced teacher to train the mind of the students, and enable them to think critically and correctly. the most important question here is that how to develop such a crucial ability? this study examines a new way to the development of critical thinking utilizing critical discourse analytical tools. to attain this goal, two classes of senior english la...

Selective expression of the Cre recombinase in late-stage thymocytes using the distal promoter of the Lck gene.

Transgenic mouse lines were generated that express the Cre recombinase under the control of the distal promoter of the mouse Lck gene. Cre recombination in four of these lines of transgenic mice was characterized at the single cell level using ROSA26-regulated loxP-Stop-loxP-betageo and loxP-Stop-loxP-YFP reporter mouse lines. Two of the lines showed T cell-restricted Cre recombination, whereas...

Lck Promoter of the in Late-Stage Thymocytes Using the Distal Selective Expression of the Cre Recombinase