Giant Reverse Transcriptase-Encoding Transposable Elements at Telomeres
نویسندگان
چکیده
منابع مشابه
Reverse transcriptase at bacterial telomeres.
I n the past two decades, intense efforts have been devoted to uncovering the mechanisms responsible for the maintenance of telomeres in eukaryotic cells. These efforts have led to the identification of an unusual reverse transcriptase (RT), named telomerase, that uses an integral RNA subunit as template to synthesize a short reiterated sequence at the ends of eukaryotic chromosomes (Fig. 1A) (...
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In a recent report in Trends in Genetics, Gao and Voytas [1] described a new family of integrase genes that were identified in diverse eukaryotic species, including slime mold, Caenorhabditis elegans, C. briggsae, zebrafish, Takifugu rubripes, Xiphophorus maculates, cow, dog and humans. These genes potentially encode proteins containing w400 amino acids with homology to retroviral integrases an...
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ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 2017
ISSN: 0737-4038,1537-1719
DOI: 10.1093/molbev/msx159