Ginsenosides-Rbl exerts beneficial effects on left ventricular dysfunction and remodelling early after myocardial infarction
نویسندگان
چکیده
منابع مشابه
Nebivolol exerts beneficial effects on endothelial function, early endothelial progenitor cells, myocardial neovascularization, and left ventricular dysfunction early after myocardial infarction beyond conventional β1-blockade.
OBJECTIVES The aim of this study was to investigate whether nebivolol has added effects on left ventricular (LV) dysfunction and remodeling early after myocardial infarction (MI) beyond its β₁-receptor-blocking properties. BACKGROUND Nebivolol is a third-generation selective β₁-adrenoreceptor antagonist that stimulates endothelial cell nitric oxide (NO) production and prevents vascular reduce...
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In acute myocardial infarction (MI), reactive oxygen species (ROS) are generated in the ischaemic myocardium especially after reperfusion. ROS directly injure the cell membrane and cause cell death. However, ROS also stimulate signal transduction to elaborate inflammatory cytokines, e.g. tumour necrosis factor-alpha (TNF-alpha), interleukin (IL)-1beta and -6, in the ischaemic region and surroun...
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Ventricular remodelling is the main trigger of the development of heart failure. Therefore, the reduction of structural remodelling is known to prevent the development of heart failure. The aim of the present study was to investigate the effects of OMACOR, a well known mixture of EPA and DHA in an experimental model of heart failure induced by occlusion of left descending coronary artery and th...
متن کاملProgressive left ventricular dysfunction and remodeling after myocardial infarction.
ventricular volume. Therefore, a cutpoint of 8% for an increase in EDVI was chosen. We agree with Dr Armstrong that the results of discriminant analysis should be applied with caution, as outlined in the discussion on page 762. Of particular importance are the baseline characteristics of the study population, which include age as well as other variables (Table 1).' Multivariate discriminant ana...
متن کاملProgressive Left Ventricular Dysfunction and Remodeling After Myocardial Infarction
ventricular volume. Therefore, a cutpoint of 8% for an increase in EDVI was chosen. We agree with Dr Armstrong that the results of discriminant analysis should be applied with caution, as outlined in the discussion on page 762. Of particular importance are the baseline characteristics of the study population, which include age as well as other variables (Table 1).' Multivariate discriminant ana...
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ژورنال
عنوان ژورنال: Heart
سال: 2011
ISSN: 1355-6037
DOI: 10.1136/heartjnl-2011-300867.131