Glucocorticoids and osteocyte autophagy
نویسندگان
چکیده
منابع مشابه
Parathyroid Hormone (PTH) Induces Autophagy to Protect Osteocyte Cell Survival from Dexamethasone Damage
BACKGROUND Glucocorticoids (GC) have direct adverse effects on osteocytes, the most abundant bone cell type, and play an important role in osteonecrosis of the femoral head (ONFH). Teriparatide has been reported to be an effective treatment for ONFH. However, the underlying mechanism is unclear. MATERIAL AND METHODS An osteocyte cell line, MLO-Y4, was used under various doses of dexamethasone (...
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ژورنال
عنوان ژورنال: Bone
سال: 2013
ISSN: 8756-3282
DOI: 10.1016/j.bone.2013.01.034