Good Estrogen Bad Estrogen

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Good Estrogen Bad Estrogen

Estrogen is a term used for a variety of natural and synthetic hormones that influence the growth and function of many tissues, particularly those of the male and female reproductive systems. Estrogen plays a role in several cancers, especially breast and endometrial cancers and possibly prostate and colon cancers. The human diet contains estrogenic compounds that can bind to estrogen receptors...

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Estrogen: good, bad, or both?

S ex differences in the prevalence and progression of numerous cardiovascular diseases are well documented, with males typically exhibiting greater severity and progression of disease compared with age-matched females. In contrast, females are more likely to develop autoimmune disease compared with age-matched males, both clinically and experimentally. Nevertheless, there is growing evidence th...

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Estrogen--the good, the bad, and the unexpected.

1 Introduction In the last decade or so, our knowledge of the roles of the steroids referred to as 'sex hormones' namely testosterone and estradiol, has undergone a quiet revolution. In the first place, models of androgen and estrogen insufficiency, whether they be natural or engineered, have revealed new and unexpected roles for sex steroids, some of which have nothing to do with reproduction....

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Effects of treadmill exercise training on cerebellar estrogen and estrogen receptors, serum estrogen, and motor coordination performance of ovariectomized rats

Objective(s): The present study aims at examining the motor coordination performance, serum and cerebellar estrogen, as well as ERβ levels, of ovariectomized rats (as menopausal model) following regular exercise. Materials and Methods:Ten female Sprague Dawley ratsaged 12 weeks old were randomly divided into two groups; all of which underwent ovariectomy. The first group was treated with regula...

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Estrogen receptor interaction with estrogen response elements.

The estrogen receptor (ER) is a ligand-activated enhancer protein that is a member of the steroid/nuclear receptor superfamily. Two genes encode mammalian ER: ERalpha and ERbeta. ER binds to specific DNA sequences called estrogen response elements (EREs) with high affinity and transactivates gene expression in response to estradiol (E(2)). The purpose of this review is to summarize how natural ...

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 2000

ISSN: 0091-6765,1552-9924

DOI: 10.1289/ehp.108-a416a