Granular cell tumor in the central nervous system of a ferret (Mustela putorius furo) - a case report

A granular cell tumor (GCT) in the central nervous system (CNS) of a ferret is rare finding. In this case cerebral GCT described 5-year-old castrated female ferret. The animal developed lameness right hind leg which progreseed to total ataxia. died and necropsy revealed mass medial caudal part left frontal lobe brain. Based on histological imunohistochemical findings, was diagnosed as tumor. Immunohistochemically, cells were diffusely positive for vimentin neuron-specific enolase (NSE) weakly focal reactivity S-100 protein seen. Neoplastic did not express cytokeratins glial fibrillary acidic (GFAP). Although immunohistochemistry performed, histogenesis remains unsolved controversial.