Graphene coating onto mechanical heart valve prosthesis and resistance to flow dynamics

A mechanical analysis of the closed Hancock heart valve prosthesis.

In order to obtain mechanical specifications for the design of an artificial leaflet valve prosthesis, a geometrically non-linear numerical model is developed of a closed Hancock leaflet valve prosthesis. In this model, the fibre reinforcement of the leaflet and the viscoelastic properties of frame and leaflets are incorporated. The calculations are primarily restricted to 1/6 part of the valve...

Warfarin resistance in a patient with mechanical valve prosthesis.

he term warfarin resistance is usually reserved for patients who require warfarin in excess of 20 mg/day to maintain the International Normalized Ratio (INR) within the therapeutic range. It is usually encountered at the start of therapy, however, it may also occur in patients who have been already on warfarin therapy. Both diet and the co-administration of certain drugs can have a marked effec...

New Aortic Valve Prosthesis - A Concept and Realization of Mechanical Valve Prosthesis Compatible with the Flow in Aorta

A new type of mechanical aortic valve prosthesisTornado-compatible valve (TCV) is worked out basing on the principle of hydrodynamic compatibility with the swirling Tornado-like blood flow present in the heart cavities and main arteries. The design and profile of the TCV were calculated basing on the exact solution of the non stationary hydrodynamic equations for the class of self organizing To...

A mechanical prosthesis for pulmonary valve replacement?

Fulminant thrombosis of mechanical mitral valve prosthesis.

In patients with prosthetic heart valves non-cardiac surgery may require temporary discontinuation of oral anticoagulation. Although the risk of valve related thromboembolic complications may generally be only slightly increased during the short perioperative period, in the presence of certain risk factors, replacement of oral anticoagulation with heparin is recommended. In the presented patien...