Half-life modeling of basic fibroblast growth factor released from growth factor-eluting polyelectrolyte multilayers
نویسندگان
چکیده
منابع مشابه
Toward surgical angiogenesis using slow-released basic fibroblast growth factor.
OBJECTIVE Therapeutic angiogenesis using basic fibroblast growth factor (bFGF) in coronary artery disease has been documented in a number of papers. However, the effectiveness is discrepant among documents. In this study, we evaluated the distribution of bFGF in the rat heart by different administration methods, and investigated the efficacy of slow-released administration of bFGF using biodegr...
متن کاملEffect of Basic Fibroblast Growth Factor on Achilles Tendon Healing in Rabbit
BACKGROUND Tendon injuries are common and it takes a long time for an injured tendon to heal. Adverse phenomena such as adhesion and rupture are associated with these injuries. Finding a method to reduce the time required for healing whichimproves the final outcome, will lead to decreased frequency and intensity of adverse consequences. This study was designed to investigate the effects ...
متن کاملFibroblast Growth Factor-1 vs. Fibroblast Growth Factor-2 in Ischemic Skin Flap Survival in a Rat Animal Model
BACKGROUND One of the main challenges in skin flap surgery is tissue ischemia and following necrosis. The present study compares the effects of fibroblast growth factors 1 and 2 on increasing cutaneous vasculature, improving ischemia, and preventing distal necrosis in ischemic skin flaps in rat model. METHODS Thirty rats were allocated into 3 groups (n=10) and 2×8 cm dorsal rando...
متن کاملThe mouse int-2 gene exhibits basic fibroblast growth factor activity in a basic fibroblast growth factor-responsive cell line.
The int-2 protein is related to basic fibroblast growth factor (bFGF) by amino acid sequence homology. To assess its biological activity, we constructed retroviral vectors containing four variants of mouse int-2 complementary DNA under the transcriptional control of the beta-actin promoter and tested their effects on human SW13 adrenal cortical tumor cells. This cell line specifically requires ...
متن کاملGrowth Factor in Children with Cyanotic Congenital Heart Vascular Endothelial Growth Factor and Basic Fibroblast
J Thorac Cardiovasc Surg Flavian M. Lupinetti K. Jones, Ronald G. Grifka, Frank Cecchin, David J. Owens, Collette Fearneyhough and Sandra L. Starnes, Brian W. Duncan, James M. Kneebone, Geoffrey L. Rosenthal, Thomas DISEASE GROWTH FACTOR IN CHILDREN WITH CYANOTIC CONGENITAL HEART VASCULAR ENDOTHELIAL GROWTH FACTOR AND BASIC FIBROBLAST http://jtcs.ctsnetjournals.org/cgi/content/full/119/3/534 th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2021
ISSN: 2045-2322
DOI: 10.1038/s41598-021-89229-w