HCMV-Mediated Interference of Bortezomib-Induced Apoptosis in Colon Carcinoma Cell Line Caco-2
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چکیده
منابع مشابه
Sulphation of lithocholic acid in the colon-carcinoma cell line CaCo-2.
High levels of bile acids in the colon may correlate with an increased risk of colon cancer, but the underlying mechanisms are not known. Proteoglycan structures have been shown to change when human colon cells differentiate in vitro. The expression of [(35)S]sulphated molecules was used as a phenotypic marker to study the effects of bile acids on the human-colon-carcinoma cell line CaCo-2. [(3...
متن کاملAbsorption and metabolism of biologically active genistein derivatives in colon carcinoma cell line (Caco-2).
Several genistein derivatives comprising an isoflavonoid skeleton substituted with an alkyl chain and a sugar moiety show ability to inhibit proliferation of cancer cells in vitro at the concentration several-fold lower than genistein. In our previous studies we shown that these compounds influenced the mitotic spindle, blocked the cell cycle and induced apoptosis. The purpose of this study was...
متن کاملAntitumor and antioxidant activity of Triticum Aestivum against CACO-2 cell line induced colon cancer
Plant-based diet supplements help the prevention and therapy of several kinds of cancer because they contain micronutrients, which exhibit chemopreventive and chemotherapeutic activities. In present study invitro cytotoxic effect of wheat grass was evaluated on Caco2 cell line by MTT assay. Further antitumor and antioxidant activity of wheatgrass was evaluated against the Caco2 cell line induce...
متن کاملButyrate induced Caco-2 cell apoptosis is mediated via the mitochondrial pathway.
BACKGROUND During the process of tumorigenesis most colon cancer cells acquire resistance to apoptosis. The short chain fatty acid butyrate is well established as an antitumour agent which selectively induces apoptosis in colon cancer cells but not in normal intestinal epithelial cells. AIMS To analyse the signalling pathway of butyrate induced apoptosis. METHODS Using Caco-2 cells we focus...
متن کاملEpigallocatechin gallate (EGCG) inhibits the sulfation of 1-naphthol in a human colon carcinoma cell line, Caco-2.
We have previously reported that epigallocatechin gallate (EGCG) strongly inhibits the in vitro phenol sulfotransferase (P-ST) activity of a human colon carcinoma cell line, Caco-2. In the present study, we examined the ability of EGCG to inhibit the sulfation of 1-naphthol in intact Caco-2 cells. Sulfation of 1-naphthol was detected in Caco-2 cells after 2 h of incubation, and was observed to ...
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ژورنال
عنوان ژورنال: Viruses
سال: 2021
ISSN: 1999-4915
DOI: 10.3390/v13010083