HCN Regulates Cellular Processes through Posttranslational Modification of Proteins by S-cyanylation
نویسندگان
چکیده
منابع مشابه
Posttranslational modification of vaccinia virus proteins.
approved: .6'17 Dr. Dennis E. Hruby Co-translational covalent attachment of myristic acid to the aminoterminal glycine residue of a variety of cellular, viral and oncoproteins is, in many instances, required for full expression of their biological activity. Within the infected cell, vaccinia virus (VV), the prototype member of the Poxviridae, expresses several myristylated proteins. One of thes...
متن کاملPosttranslational modification of proteins by isoprenoids in mammalian cells.
Isoprenylation is a posttranslational modification that involves the formation of thioether bonds between cysteine and isoprenyl groups derived from pyrophosphate intermediates of the cholesterol biosynthetic pathway. Numerous isoprenylated proteins have been detected in mammalian cells. Those identified include K-, N-, and H-p21ras, ras-related GTP-binding proteins such as G25K (Gp), nuclear l...
متن کاملLabeling proteins with small molecules by site-specific posttranslational modification.
We report here the development of a general strategy for site-specific labeling of proteins with small molecules by posttranslational modification enzyme, phosphopantetheinyl transferase Sfp. The target proteins are expressed as fusions to the peptide carrier protein (PCP) excised from nonribosomal peptide synthetase, and Sfp catalyzes the covalent modification of a specific serine residue on P...
متن کاملChemical and Functional Aspects of Posttranslational Modification of Proteins
This paper reviews the chemical and functional aspects of the posttranslational modifications of proteins, which are achieved by the addition of various groups to the side chain of the amino acid residue backbone of proteins. It describes the main prosthetic groups and the interaction of these groups and the apoenzyme in the process of catalysis, using pyridoxal catalysis as an example. Much at...
متن کاملAnalysis of expression and posttranslational modification of proteins during hypoxia.
The cellular responses to hypoxia are complex and characterized by alterations in the expression of a number of genes, including stress-related genes and corresponding proteins that are necessary to maintain homeostasis. The purpose of this article is to review previous and recent studies that have examined the changes in the expression and posttranslational modification of proteins in response...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Plant Physiology
سال: 2018
ISSN: 0032-0889,1532-2548
DOI: 10.1104/pp.18.01083