HDL in innate and adaptive immunity

SPOTLIGHT REVIEW HDL in innate and adaptive immunity

During infections or acute conditions high-density lipoproteins cholesterol (HDL-C) levels decrease very rapidly and HDL particles undergo profound changes in their compositionand function. These changes are associatedwith poor prognosis following endotoxemia or sepsis and data from genetically modified animal models support a protective role for HDL. The same is true for some parasitic infecti...

Bridging Innate and Adaptive Immunity

The Nobel Prize in Physiology or Medicine for 2011 to Jules Hoffmann, Bruce Beutler, and the late Ralph Steinman recognizes accomplishments in understanding and unifying the two strands of immunology, the evolutionarily ancient innate immune response and modern adaptive immunity.

Innate and adaptive immunity in human epilepsies

Inflammatory mechanisms have been increasingly implicated in the origin of seizures and epilepsy. These mechanisms are involved in the genesis of encephalitides in which seizures are a common complaint. Experimental and clinical evidence suggests different inflammatory responses in the brains of patients with epilepsy depending on the etiology. In general, activation of both innate and adaptive...

HDL and innate immunity: a tale of two apolipoproteins.

Trauma, Sepsis, Innate, Adaptive Immunity and Inflammation

Introduction: This review paper covered, trauma, sepsis, innate, adaptive immunity and inflammation along with anxiety, and depression that occurs both in women with asthma, traumatic children and adult patients. Materials and Methods: This is a review article. Areas covered include immune function changes, which can lead to both trauma and pro-inflammatory activation known as systemic inflamma...