Hepatic tissue engineering for adjunct and temporary liver support: Critical technologies
نویسندگان
چکیده
منابع مشابه
Assessing porcine liver-derived biomatrix for hepatic tissue engineering.
Acellular, biologically derived matrices such as small intestinal submucosa have been extensively utilized to induce tissue regeneration and remodeling of connective tissue, vascular grafts, and urinary bladder; however, decellularized scaffolds have not been explored for their potential utility in hepatic tissue engineering. In the case of both extracorporeal hepatocyte-based devices and impla...
متن کاملTemporary Liver Support : Current Concepts
463 Liver failure occurs either as acute liver failure (ALF) developing de novo or as acute decompensation of chronic liver disease (ACLF). The clinical manifestations are fairly similar characterised by multiorgan dysfunction characterised by encephalopathy (HE), hypotension, and renal failure (HRS).1,2 Unlike chronic decompensation of end-stage liver disease, ALF and ACLF are potentially reve...
متن کاملMicroscale technologies for tissue engineering and biology.
Microscale technologies are emerging as powerful tools for tissue engineering and biological studies. In this review, we present an overview of these technologies in various tissue engineering applications, such as for fabricating 3D microfabricated scaffolds, as templates for cell aggregate formation, or for fabricating materials in a spatially regulated manner. In addition, we give examples o...
متن کاملHepatic Tissue Engineering
Liver disease afflicts over 600 million people worldwide, 30 million of whom are Americans. Liver disease leads to the death of over 40,000 individuals in the United States every year. Liver failure can be generally separated into two major categories: fulminant hepatic failure, also referred to as acute liver failure, and chronic hepatic failure resulting from chronic end-stage liver disorders...
متن کاملPig liver perfusion and other methods of temporary liver support.
abnormal results for these tests may not bleed and blood transfusion is not entirely free from risk. Hence no transfusion is given to correct the defects unless certain positive indications are present-such as daily deterioration in test results; damage to blood vessels; and if bleeding has occurred. The amount and type of transfusion fluid to be used follows the generally accepted principles f...
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ژورنال
عنوان ژورنال: Liver Transplantation
سال: 2004
ISSN: 1527-6465,1527-6473
DOI: 10.1002/lt.20229