Hepatitis A outbreak among MSM in Berlin due to low vaccination coverage: Epidemiology, management, and successful interventions

ObjectivesTo describe the characteristics of a large hepatitis A virus (HAV) outbreak among men who have sex with (MSM) in Berlin and to assess impact measures implemented.MethodsCases laboratory-confirmed, symptomatic HAV infection notified Berlin, Germany between August 2016 February 2018 were analysed using routine enhanced surveillance data including genotyping results. Several studies involving different groups participants conducted further investigate outbreak, surveys on knowledge practices vaccination physicians coverage determinants status MSM. The implemented categorized by target group Gantt chart. To their impact, health insurance uptake analysed, comparing other federal states.ResultsDuring period, total 222 cases reported (of which 91 sequence-confirmed), peak case numbers January 2017. Physicians aware existing recommendations, but 756 MSM was low, 32.7% being completely vaccinated 17.3% incompletely before 2017 associated born (odds ratio 2.36) HIV-positive 1.80). monovalent increased 164% from males compared 7% states.ConclusionsMultiple targeting community, physicians, public increase successfully implemented. prevent future outbreaks, we recommend monitoring MSM, promoting awareness recommendations ensuring access for foreign-born young