Hepatocyte tissue factor contributes to the hypercoagulable state in a mouse model of chronic liver injury
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چکیده
منابع مشابه
from linguistics to literature: a linguistic approach to the study of linguistic deviations in the turkish divan of shahriar
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James P. Luyendyk, Glenn H. Cantor, Daniel Kirchhofer, Nigel Mackman, Bryan L. Copple, and Ruipeng Wang Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas; Discovery Toxicology, Bristol-Myers Squibb, Princeton, New Jersey; Department of Protein Engineering, Genentech, South San Francisco, California; and Division of Hematology/O...
متن کاملTissue factor-dependent coagulation contributes to alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice.
Separation of concentrated bile acids from hepatic parenchymal cells is a key function of the bile duct epithelial cells (BDECs) that form intrahepatic bile ducts. Using coimmunostaining, we found that tissue factor (TF), the principal activator of coagulation, colocalized with cytokeratin 19, a marker of BDECs in the adult mouse liver. BDEC injury induced by xenobiotics such as alpha-naphthyli...
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ژورنال
عنوان ژورنال: Journal of Hepatology
سال: 2016
ISSN: 0168-8278
DOI: 10.1016/j.jhep.2015.08.017