Hepatostat: Liver regeneration and normal liver tissue maintenance
نویسندگان
چکیده
منابع مشابه
Liver regeneration after liver transplantation.
BACKGROUND/PURPOSE The liver has a remarkable capacity to regenerate after injury or resection. The aim of this review is to outline the mechanisms and factors affecting liver regeneration after liver transplantation. METHODS Relevant studies were reviewed using Medline, PubMed and Springer databases. RESULTS A variety of cytokines (such as interleukin-6 and tumor necrosis factor-α), growth...
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Liver sinusoidal endothelial cells (LSECs) have long been noted to contribute to liver regeneration after liver injury. In normal liver, the major cellular source of HGF is the hepatic stellate cell, but after liver injury, HGF expression has been thought to increase markedly in proliferating LSECs. However, emerging data suggest that even after injury, LSEC expression of HGF does not increase ...
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Platelets are the smallest structures in circulating blood and have a convex disc construction with an equatorial diameter of 2-3 microns and have no nucleus. They are derived from megakaryocytes in the bone marrow. Following their normal life span of 8-10 days, they are removed from the circulation when passing through the spleen. Platelets have three types of secretory granules, i.e., alpha-g...
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Background and purpose: Artificial sweeteners are increasingly used in food products, so, it is necessary to study the effects of these additives on liver. Materials and methods: In this experimental study, 30 immature male rats were divided into five groups (n=6 per group) and acesulfame k at 50, 100, 200, and 400 mg/kg were injected intraperitoneally to all groups for 30 days. One and 30 d...
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For the development of innovative cell-based liver directed therapies, e.g. liver tissue engineering, the use of stem cells might be very attractive to overcome the limitation of donor liver tissue. Liver specific differentiation of embryonic, fetal or adult stem cells is currently under investigation. Different types of fetal liver (stem) cells during development were identified, and their adv...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2017
ISSN: 0270-9139
DOI: 10.1002/hep.28988