HER2 Targeted Molecular MR Imaging Using a De Novo Designed Protein Contrast Agent
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چکیده
منابع مشابه
HER2 Targeted Molecular MR Imaging Using a De Novo Designed Protein Contrast Agent
The application of magnetic resonance imaging (MRI) to non-invasively assess disease biomarkers has been hampered by the lack of desired contrast agents with high relaxivity, targeting capability, and optimized pharmacokinetics. We have developed a novel MR imaging probe targeting to HER2, a biomarker for various cancer types and a drug target for anti-cancer therapies. This multimodal HER20tar...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0018103