HIERARCHY OF PROGNOSTIC FACTORS FOR CORNEAL ALLOGRAFT SURVIVAL
نویسندگان
چکیده
منابع مشابه
Promotion of corneal allograft survival with leflunomide.
PURPOSE The efficacy of the antirejection drug leflunomide was evaluated in a rat model of penetrating keratoplasty. METHODS Corneal grafts from inbred Lewis rats were transplanted orthotopically to inbred Wistar-Furth (WF) recipients. WF rats received either Leflunomide (HWA 486), the active metabolite of leflunomide (A77-1726A), or cyclosporin A, administered orally beginning 2 days before ...
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PURPOSE The precise role of antibodies in corneal transplantation is ambiguous, with evidence to support as well as repudiate their involvement in graft rejection. Accordingly, this study was undertaken to investigate the direct contribution of donor-specific antibodies to corneal graft rejection. METHODS Serum samples from CB6F1 rejecters of orthotopically grafted C3H/Hej corneas were tested...
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Background: Correlations between bone marrow, heart, kidney, liver, skin and lung transplant rejection or survival with human cytokine gene polymorphisms have been described. There are also reports about the role of cytokines and Tumor Necrosis Factors-Alpha (TNF-α) on corneal transplant in animal models. Further studies are needed to clarify the role of cytokines in corneal allograft rejection...
متن کاملOral immunisation as a strategy for enhancing corneal allograft survival.
AIMS To determine optimal conditions for enhancing corneal allograft survival through oral administration of donor specific corneal cells. METHODS A mouse model of penetrating keratoplasty was used to evaluate the efficacy and optimal conditions for preventing immunological rejection of corneal allografts. C3H corneal grafts were transplanted orthotopically to CB6F1 recipients and represented...
متن کاملCombined corneal allotransplantation and vitreoretinal surgery using an Eckardt temporary keratoprosthesis: analysis for factors determining corneal allograft survival
PURPOSE To evaluate the outcome of corneal allotransplantation in combined penetrating keratoplasty and vitreoretinal surgery using a temporary keratoprosthesis, and to determine the factors affecting corneal allograft survival. METHODS We reviewed the medical charts of eleven patients who had undergone combined corneal allotransplantation and pars plana vitrectomy using an Eckardt temporary ...
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ژورنال
عنوان ژورنال: Australian and New Zealand Journal of Ophthalmology
سال: 1987
ISSN: 0814-9763,1440-1606
DOI: 10.1111/j.1442-9071.1987.tb01777.x