High production of ectoine from aspartate and glycerol by use of whole-cell biocatalysis in recombinant Escherichia coli
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چکیده
منابع مشابه
High production of ectoine from aspartate and glycerol by use of whole-cell biocatalysis in recombinant Escherichia coli
BACKGROUND Recently, the compatible solute 1, 4, 5, 6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid (ectoine) has attracted considerable interest due to its great potential as a protecting agent. To overcome the drawbacks of high salinity in the traditional bioprocess of ectoine using halophilic bacteria, various attempts have been made to engineer ectoine biosynthesis in nonhalophilic bacter...
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BACKGROUND Whole-cell redox biocatalysis has been intensively explored for the production of valuable compounds because excellent selectivity is routinely achieved. Although the cellular cofactor level, redox state and the corresponding enzymatic activity are expected to have major effects on the performance of the biocatalysts, our ability remains limited to predict the outcome upon variation ...
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ژورنال
عنوان ژورنال: Microbial Cell Factories
سال: 2015
ISSN: 1475-2859
DOI: 10.1186/s12934-015-0238-0