High-resolution 3D structures reveal the biological functions of reoviruses
نویسندگان
چکیده
منابع مشابه
High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation.
IgM is the first antibody produced during the humoral immune response. Despite its fundamental role in the immune system, IgM is structurally only poorly described. In this work we used X-ray crystallography and NMR spectroscopy to determine the atomic structures of the constant IgM Fc domains (Cµ2, Cµ3, and Cµ4) and to address their roles in IgM oligomerization. Although the isolated domains s...
متن کاملthe role of task-based techniques on the acquisition of english language structures by the intermediate efl students
this study examines the effetivenss of task-based activities in helping students learn english language structures for a better communication. initially, a michigan test was administered to the two groups of 52 students majoring in english at the allameh ghotb -e- ravandi university to ensure their homogeneity. the students scores on the grammar part of this test were also regarded as their pre...
15 صفحه اولHigh-Resolution Crystal Structures Reveal Plasticity in the Metal Binding Site of Apurinic/Apyrimidinic Endonuclease I
Apurinic/apyrimidinic endonuclease I (APE1) is an essential base excision repair enzyme that catalyzes a Mg²⁺-dependent reaction in which the phosphodiester backbone is cleaved 5' of an abasic site in duplex DNA. This reaction has been proposed to involve either one or two metal ions bound to the active site. In the present study, we report crystal structures of Mg²⁺, Mn²⁺, and apo-APE1 determi...
متن کاملtreating refractory hypertension: renal denervation with high-resolution 3d-angiography
a 53-year-old male was referred to our department for refractory primary hypertension. despite high doses of 6 anti-hypertensive drugs, ambulatory monitoring of blood pressure (bp) revealed a mean bp of 160/90 mmhg. under local anaesthesia, renal denervation with radiofrequency was performed supported by high-resolution 3d angiography, which helped confirm the position of the applications in a ...
متن کاملStatistical universals reveal the structures and functions of human music.
Music has been called "the universal language of mankind." Although contemporary theories of music evolution often invoke various musical universals, the existence of such universals has been disputed for decades and has never been empirically demonstrated. Here we combine a music-classification scheme with statistical analyses, including phylogenetic comparative methods, to examine a well-samp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Virologica Sinica
سال: 2013
ISSN: 1674-0769,1995-820X
DOI: 10.1007/s12250-013-3341-6