High-speed Atomic Force Microscopy for Capturing Dynamic Behavior of Biological Molecules
نویسندگان
چکیده
منابع مشابه
High-Speed Atomic Force Microscopy for Studying the Dynamic Behavior of Protein Molecules at Work
In the quest for the mechanism of protein functions, various key techniques and instruments have been developed. This is an era when scrutinizing a certain protein from various angles is becoming possible through combined knowledge of its structure and function. However, it is necessary to link these different aspects of a protein along a time axis, but no technology is available for tracing a ...
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High-speed atomic force microscopy (HS-AFM) has been developed as a nano-dynamics visualization technique. This microscopy permits direct observation of structure dynamics and dynamic processes of biological molecules in physiological solutions, at a subsecond to sub-100 ms temporal resolution and an ∼2 nm lateral and a 0.1 nm vertical resolution. Importantly, tip-sample interactions do not dis...
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The atomic force microscope (AFM) is unique in its capability to capture high-resolution images of biological samples in liquids. This capability will become more valuable to biological sciences if AFM additionally acquires an ability of high-speed imaging, because 'direct and real-time visualization' is a straightforward and powerful means to understand biomolecular processes. With conventiona...
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Many applications in materials science, life science and process control would benefit from atomic force microscopes (AFM) with higher scan speeds. To achieve this, the performance of many of the AFM components has to be increased. In this work, we focus on the cantilever sensor, the scanning unit and the data acquisition. We manufactured 10 microm wide cantilevers which combine high resonance ...
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ژورنال
عنوان ژورنال: Hyomen Kagaku
سال: 2010
ISSN: 0388-5321,1881-4743
DOI: 10.1380/jsssj.31.405