High-throughput subcellular protein localization using cell arrays
نویسندگان
چکیده
منابع مشابه
High-throughput subcellular protein localization using cell arrays.
Accomplishment of the human and mouse genome projects resulted in accumulation of extensive gene sequence information. However, the information about the biological functions of the identified genes remains a bottleneck of the post-genomic era. Hence, assays providing simple functional information, such as localization of the protein within the cell, can be very helpful in the elucidation of it...
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ORGANIZATION. Section 1. We first provide the motivation for prediction of protein subcellular localization sites, as well as discuss changes being brought about by progress in proteomics. Section 2. After that, we describe the biology of protein subcellular location. In particular, we explain the principle of protein sorting signals. Section 3. Then we present several experimental techniques f...
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ژورنال
عنوان ژورنال: Biochemical Society Transactions
سال: 2005
ISSN: 0300-5127,1470-8752
DOI: 10.1042/bst20051407