Histologic prognostic indicators in hepatocellular carcinoma

Prognostic molecular markers in hepatocellular carcinoma (Review article

Hepatocellular carcinoma (HCC) is the 5th commonest malignancy worldwide and is the third most common cause of cancer-related death. The prevalence is different in the world. The ability to predict patients at higher risk of recurrence and with a poor prognosis would help to guide surgical and chemotherapeutic treatment according to individual risk. As understanding of hepatocarcinogenesi...

Hepatocellular Carcinoma in Sheep

Hepatocellular carcinoma in a sheep

At necropsy of a five-year-old sheep, a pear shaped, lobular yellow-brownish mass measuring about 12 ×15 × 20 cm was found to involve the right hepatic lobe. Microscopic examination revealed two trabecularand solid patterns of neoplastic hepatocytes. In solid pattern, there were numerous tumoral giant cells thatcontain one or more large hyperchromatic bizarre-shaped nuclei scattered among clust...

Prognostic Predictor for Hepatocellular Carcinoma

Hepatocelluar carcinoma (HCC), the sixth most prevalent cancer type, ranks the third leading cause of cancer-related mortality worldwide (Forner et al., 2012), especially in many countries of Asia (Fazeli et al., 2012). Although surgical resection is considered to be the most effective therapeutic method for treatment of patients with primary hepatic carcinoma, the high recurrence rate and earl...

Prognostic indicators in differentiated thyroid carcinoma.

BACKGROUND Thyroid cancer ranges from well-differentiated lesions with an excellent prognosis to anaplastic carcinoma, which is almost uniformly fatal. Thus, methods to assess the behavior of thyroid malignancies are necessary to arrive at appropriate treatment decisions. METHODS We discuss the factors that affect the prognosis of patients with well-differentiated thyroid malignancies, includ...