Histological Features and Predictors of Early Relapse in Patients of Ulcerative Colitis

Objective: To determine the proportion of histological features and feature predicting frequency elapse in known patients ulcerative colitis. Methodology: One hundred ninety cases each had endoscopic colonic biopsies from rectum, distal colon, proximal colon. Study Design: Retrospective Case series Setting: Sheikh Zayed Hospital Lahore, Department Histopathology, February 25, 2016, to 2017. Results: The majority complained generalized abdominal pain (55.3%). commonest is cryptitis 189(99.5%). Majority with basal plasmacytosis 38(42.2%) crypt abscess 36(29.8%) relapsed at 4th month. Conclusion: Histological are prognostic importance. A greater chance relapse can be predicted increased number plasma cells cryptitis. These findings will help further management colitis patients. Keywords: Inflammatory bowel disease, Ulcerative colitis, Remission, Relapse