Histopathological changes in androgenized ovaries are recovered by melatonin treatment
نویسندگان
چکیده
منابع مشابه
Polycystic ovary syndrome resembling histopathological alterations in ovaries from prenatal androgenized female rats
BACKGROUND The polycystic ovary syndrome (PCOS) affects approximately 6-10% of women of reproductive age and is characterized by chronic anovulation and hyperandrogenism. However, a comprehensive understanding of the mechanisms that dictate androgen overproduction is lacking, which may account for inconsistencies between measures of androgen excess and clinical presentation in individual cases....
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OBJECTIVES 2-Nitropropane (2-NP) is mutagenic in a number of short-term mutagenicity assays in vitro and in vivo, and is a potent hepatocarcinogen in rats. Many studies have determined that differences in the metabolism and disposition of the chemicals that produce mutagenicity were not responsible for their observed carcinogenic differences, but that carcinogenicity correlated with the ability...
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متن کاملHistopathological findings of the ovaries in anovulatory women.
Wedge resection of the ovary was carried out in 45 anovulatory women to study the correlation between the degree of disturbance of ovulation and the histopathological findings. Polycystic ovary was always found in patients with anovulatory cycles. The ovaries in grade 1 amenorrhea showing withdrawal bleeding in response to gestagen alone belonged to the nonspecific type, polycystic type and scl...
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ژورنال
عنوان ژورنال: International Journal of Experimental Pathology
سال: 2018
ISSN: 0959-9673
DOI: 10.1111/iep.12283