Hospitalized Patients With Atrial Fibrillation and a High Risk of Stroke Are Not Being Provided With Adequate Anticoagulation

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Hospitalized patients with atrial fibrillation and a high risk of stroke are not being provided with adequate anticoagulation.

OBJECTIVES The purpose of this study was to determine both treatment gaps and predictors of warfarin use in atrial fibrillation (AF) patients enrolled in a national multicenter study. BACKGROUND The National Anticoagulation Benchmark Outcomes Report (NABOR) is a performance improvement program designed to benchmark anticoagulation prophylaxis, treatment, and outcomes among participating hospi...

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Bleeding risk, physical functioning and non-use of anticoagulation among patients with stroke and atrial fibrillation.

BACKGROUND Atrial fibrillation (AF) is common among people with stroke. Anticoagulation medications can be used to manage the deleterious impact of AF after stroke, however, may not be prescribed due to concerns about post-stroke falls and decreased functioning. Thus, the purpose of this study was to identify, among people with stroke and AF, predictors of anticoagulation prescription at hospit...

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Oral anticoagulation to reduce risk of stroke in patients with atrial fibrillation: current and future therapies

Atrial fibrillation (AF) is associated with an increased incidence and severity of strokes. The burden of AF-related stroke is expected to increase in parallel with the aging of the population. Oral anticoagulation with warfarin has been the pharmacologic standard for stroke risk reduction in patients with AF. When used with close attention to dosing and monitoring, warfarin is effective prophy...

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Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin.

BACKGROUND The rate of stroke in atrial fibrillation (AF) depends on the presence of comorbid conditions and the use of antithrombotic therapy. Although adjusted-dose warfarin is superior to aspirin for reducing stroke in AF, the absolute risk reduction of warfarin depends on the stroke rate with aspirin. This prospective cohort study tested the predictive accuracy of 5 stroke risk stratificati...

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Atrial fibrillation in older patients—reducing stroke risk is not only about anticoagulation

Atrial fibrillation (AF) is associated with a five-fold increased risk of ischaemic stroke, stroke recurrence and mortality. Anticoagulant therapy may reduce the risk of recurrent stroke by approximately 60% and is more efficacious than anti-platelet agents.  However, warfarin is prescribed infrequently in older patients with AF, presumably due to concerns with haemorrhage risk. A retrospectiv...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2005

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2005.06.077