Host genetic architecture in single and multiple infections
نویسندگان
چکیده
منابع مشابه
Novel host genetic variations associated with spontaneous clearance of a single-source outbreak of HCV1b infections
BACKGROUND AND AIMS A total of 105 patients were identified as accidentally infected with hepatitis C virus genotype 1b (HCV1b) through blood transfusion from a single blood donor. This group provides a unique patient population to study host factors involved in the spontaneous clearance of HCV and disease progression. METHODS Clinical markers, HCV RNA and eight single nucleotide polymorphism...
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Under a hypothesis that the host-parasite interaction system is governed by genome-for-genome interaction, we propose a genetic model that integrates genetic information from both of the host and parasite genomes. The model can be used for mapping quantitative trait loci (QTLs) conferring the interaction between host and parasite and detecting interactions among these QTLs. A one-dimensional ge...
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ژورنال
عنوان ژورنال: Journal of Evolutionary Biology
سال: 2008
ISSN: 1010-061X
DOI: 10.1111/j.1420-9101.2008.01657.x