Human superiority is obvious but does not justify cruelty

CD93 is Selectively Expressed on Human Myeloma Cells but Not on B Lymphocytes

Background: CD93 has originally been known as a C1q receptor, and many studies have demonstrated that CD93 is expressed on hematopoietic stem cells, B cell progenitors, myeloid and monocytic cells. Moreover, CD93 is shown to be expressed on long-lived plasma cells, and CD93 deficient-mice display an impairment in plasma cell development. Objective: To investiga...

Randomization Does Not Justify Logistic Regression

The logit model is often used to analyze experimental data. However, randomization does not justify the model, so the usual estimators can be inconsistent. A consistent estimator is proposed. Neyman’s non-parametric setup is used as a benchmark. In this setup, each subject has two potential responses, one if treated and the other if untreated; only one of the two responses can be observed. Besi...

Human prion disease hypothesis does not justify the origin of bovine spongiform encephalopathy.

The word-superiority effect does not require a T-scope.

Six experiments examined the possibility of obtaining a word-superiority effect (WSE) without the use of brief stimulus exposures or a poststimulus mask. In each experiment, subjects were presented a stimulus string and two alternative strings that differed by a single letter (Reicher, 1969). The alternatives and stimulus remained in view until subjects responded, and subjects were under no pre...

Macromolecular crowding: obvious but underappreciated.

Biological macromolecules evolve and function within intracellular environments that are crowded with other macromolecules. Crowding results in surprisingly large quantitative effects on both the rates and the equilibria of interactions involving macromolecules, but such interactions are commonly studied outside the cell in uncrowded buffers. The addition of high concentrations of natural and s...