Hydroethanolic extract of Smallanthus sonchifolius leaves improves hyperglycemia of streptozotocin induced neonatal diabetic rats
نویسندگان
چکیده
منابع مشابه
Beneficial Effects of an Hydroethanolic Extract of Smallanthus Sonchifolius Leaves on the Metabolic Changes in Diabetic Rats
In this study the anti-hyperglycemic effect of the hydroethanolic extract of Smallanthus sonchifolius leaves (yacon extract) in streptozotocin-induced type 1 diabetic rats (SZT i.p, 50 mg/kg) was characterized, with emphasis on the metabolic changes found in this experimental model. Diabetic and normal rats received extract (400 mg/kg) or water by the oral route for 30 days. At the end of the t...
متن کاملAnti Diabetic Activity of Hydroethanolic Extracts of Mirabilis jalapa Leaves in Streptozotocin Induced Diabetic Rats
Mirabilis jalapa Linn (Nyctaginaceae) is a perennial herb which is widely used in Himalayan region as a traditional treatment for diabetes mellitus. The present study was designed to evaluate the Anti-hyperglycemic effect of hydroethanolic leaf extract of Mirabilis jalapa in streptozotocin induced diabetic rats. The hydroethanolic leaf extract at the concentration of 200 and 400 mg/kg of body w...
متن کاملEffect of crude extracts of leaves of Smallanthus sonchifolius (yacon) on glycemia in diabetic rats
The present study investigated the effect of crude extracts from yacon leaves, obtained by aqueous cold (YC) or hot (YH) extraction, or hydroethanolic extraction (YE), on glycemia of the diabetic (induced by streptozotocine, 50 mg/kg, ip) and nondiabetic rats. The animals were treated orally with the extracts (400 mg/kg) or water for 3, 7, 10, and 14 days. After this period, the animals were an...
متن کاملYacon (Smallanthus sonchifolius) Leaf Extract Attenuates Hyperglycemia and Skeletal Muscle Oxidative Stress and Inflammation in Diabetic Rats
The effects of hydroethanolic extract of Yacon leaves (HEYL) on antioxidant, glycemic, and inflammatory biomarkers were tested in diabetic rats. Outcome parameters included glucose, insulin, interleukin-6 (IL-6), and hydrophilic antioxidant capacity (HAC) in serum and IL-6, HAC, malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in soleus. The ra...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Tropical Medicine
سال: 2016
ISSN: 1995-7645
DOI: 10.1016/j.apjtm.2016.03.033