Hyperaldosteronism induces left atrial systolic and diastolic dysfunction

Diastolic dysfunction and left atrial volume

OBJECTIVES We examined the association between diastolic function and left atrial volume indexed to body surface area (LAVi) in a population-based study. BACKGROUND Atrial enlargement has been suggested as a marker of the severity and duration of diastolic dysfunction (DD). However, the association between DD and atrial enlargement and their individual prognostic implications in the population ...

Left ventricular diastolic dysfunction in atrial fibrillation

Systolic and diastolic dysfunction during atrial pacing in conscious dogs with left ventricular hypertrophy.

To determine the extent to which the hypertrophied left ventricle responds to the chronotropic stress induced by graded atrial pacing rates, we studied conscious, chronically instrumented dogs with severe compensated pressure overload left ventricular (LV) hypertrophy induced by aortic banding in puppies 8-10 weeks of age. At 1-2 years, dogs with severe LV hypertrophy (LV free wall/body wt rati...

Left Atrial Diastolic Dysfunction following Catheter Ablation of Atrial Fibrillation.

Radiofrequency catheter ablation (RFCA)-induced thermal injury may cause and/or worsen left atrial (LA) diastolic dysfunction leading to pulmonary hypertension and heart failure in patients with atrial fibrillation (AF), the incidence of which is probably more common than is generally realized. Biplane 2-dimensional echocardiography coupled with tissue Doppler (velocity) imaging and Doppler-der...

Left atrial systolic and diastolic function accompanying chronic rapid pacing-induced atrial failure.

The objective of this study was to examine the hypothesis that long-term, rapid atrial pacing produces a model of atrial systolic and diastolic dysfunction but does not alter ventricular function. Eight dogs were atrially paced at 400 beats/min (3:1-5:1 ventricular response) for 6 wk and subsequently instrumented with left atrial (LA) and left ventricular (LV) sonomicrometers and micromanometer...