Hyperoxia and the Immature Brain
نویسندگان
چکیده
منابع مشابه
Effects of preconditioning with intermittent normobaric hyperoxia on TNFR1 and TNFR2 expression in the rat brain
Introduction: Recent studies have shown that intermittent normobaric hyperoxia (HO) protects the rat brain from ischemia reperfusion injury. However, the exact mechanism of this kind of protection in vivo is not known. In this study, the effect of HO on expression of TNFR1 and TNFR2 in a stroke model was investigated. Methods: In this experimental study, rats were divided into 4 groups: no...
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A recent European Respiratory Journal article by WOYDA et al. [1] discussed the effect of a phosphodiesterase (PDE)4 inhibitor, cilomilast, on alveolarisation in mouse pups exposed to hyperoxia. WOYDA et al. [1] claimed in the title and concluded in the text that this treatment had the beneficial effect of preventing hyperoxia-induced impairment of alveolarisation, and proposed that PDE4 inhibi...
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BACKGROUND Human brains show widespread necrosis when death occurs after coma due to cardiac arrest, but not after hypoxic coma. It is unclear whether hypoxia alone can cause brain damage without ischemia. The relationship of blood oxygenation and vascular occlusion to brain necrosis is also incompletely defined. METHODS We used physiologically monitored Wistar rats to explore the relationshi...
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Asthma and bronchopulmonary dysplasia are prevalent diseases characterized by airway constrictor hyperresponsiveness and excessive airway smooth muscle accumulation. It is now well accepted that some alterations in airway wall architecture can increase lumenal narrowing for a given degree of smooth muscle activation. For example, increasing the thickness of the submucosal layer between airway s...
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INTRODUCTION: The interaction between neural activity and brain vasculature forms the basis of brain mapping techniques such as functional MRI, PET and optical imaging. Up until now, the interaction has primarily been considered as unidirectional. That is, neural activity can change the vascular parameters (e.g. blood oxygenation), but little attention was received as to whether gas content cha...
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ژورنال
عنوان ژورنال: Developmental Neuroscience
سال: 2016
ISSN: 0378-5866,1421-9859
DOI: 10.1159/000454917