Identification of a Functional TPH1 Polymorphism Associated With Irritable Bowel Syndrome Bowel Habit Subtypes
نویسندگان
چکیده
منابع مشابه
Diets and Irritable Bowel Syndrome
Introduction: Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder, which is characterized by the presence of abdominal pain or discomfort associated with altered bowel habits. This systematic review aimed to assess the nutritional factors (dietary patterns and food groups) associated with IBS. Methods: Articles were collected ...
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Objective: The diagnostic value of the addition of alarm symptoms in distinguishing functional from organic gastrointestinal disease remains uncertain. We aimed to establish the value of alarm features in differentiating between organic disease and irritable bowel syndrome (IBS) and functional dyspepsia (FD). Methods: A total of 568 consecutive patients (63% female; mean age 44.7 years) complet...
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of patient presentations at gastrointestinal clinics, and up to 50% or more of patients presenting with abdominal symptoms have no organic abnormality detected. The most common functional gastrointestinal conditions in Canada are irritable bowel syndrome (IBS), and functional dyspepsia or nonulcer dyspepsia (NUD). Other functional disorders may affect specific regions of the alimentary tract, s...
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Irritable bowel syndrome (IBS) is the most common functional digestive disorder, and may affect 11-20% of the adult population in industrialized countries. In accordance with Rome III criteria (2006) IBS involves abdominal pain and bowel habit disturbance, which are not explained by structural or biochemical abnormalities. Several hypotheses attempt to account for the pathophysiology of IBS, bu...
متن کاملA review on pathophysiology of irritable bowel syndrome with emphasis on the role of brain factors
Irritable bowel syndrome (IBS) is a common and chronic functional gastrointestinal disorder that causes a great burden on the individual and society. Despite many studies, there is no consent about the etiology, diagnostic and treatment method of IBS. In recent years, neurologic factors have been given attention for better understanding and management of this disorder. The aim of the present st...
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ژورنال
عنوان ژورنال: American Journal of Gastroenterology
سال: 2013
ISSN: 0002-9270
DOI: 10.1038/ajg.2013.304