Imaging-Cytology Correlation of Thyroid Nodules with Initially Benign Cytology

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Imaging-Cytology Correlation of Thyroid Nodules with Initially Benign Cytology

Objective. To determine the role of imaging-cytology correlation in reducing false negative results of fine-needle aspiration (FNA) at thyroid nodules. Methods. This retrospective study included 667 nodules 1 cm or larger in 649 patients diagnosed as benign at initial cytologic evaluation and that underwent follow-up ultrasound (US) or FNA following a radiologist's opinion on concordance betwee...

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Preoperative diagnosis of benign thyroid nodules with indeterminate cytology.

BACKGROUND Approximately 15 to 30% of thyroid nodules evaluated by means of fine-needle aspiration are not clearly benign or malignant. Patients with cytologically indeterminate nodules are often referred for diagnostic surgery, though most of these nodules prove to be benign. A novel diagnostic test that measures the expression of 167 genes has shown promise in improving preoperative risk asse...

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Large (≥3cm) thyroid nodules with benign cytology: Can Thyroid Imaging Reporting and Data System (TIRADS) help predict false-negative cytology?

BACKGROUND There is controversy about the accuracy of the fine-needle aspiration (FNA) cytology results in large sized thyroid nodules. Our aim was to evaluate the false-negative rate of FNA for large thyroid nodules and the usefulness of the Thyroid Imaging Reporting and Data System (TIRADS) in predicting false-negative cytology for large thyroid nodules with benign cytology. METHODS 632 thy...

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Thyroid Nodules with Indeterminate Cytology

To the Editor: Alexander et al. (Aug. 23 issue)1 report findings from a prospective, multicenter gene-expression classifier validation study that raises several questions. For the 265 indeterminate fine-needle aspirates they tested, the geneexpression classifier had a sensitivity of 92%, a specificity of 52%, a positive predictive value of 47%, and a negative predictive value of 93%. Why the ob...

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Ultrasound and Fine Needle Aspiration Cytology Correlation of Thyroid Nodules

Purpose: High resolution grey scale ultrasound has emerged as an initial imaging modality of choice for the evaluation of patients with thyroid enlargement. Thyroid malignancy cannot be diagnosed on ultrasonography but various sonographic features in combination can be used to predict malignancy in thyroid lesions. The aim of our study was to evaluate the diagnostic accuracy of ultrasonographic...

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ژورنال

عنوان ژورنال: International Journal of Endocrinology

سال: 2014

ISSN: 1687-8337,1687-8345

DOI: 10.1155/2014/491508