Immunotoxicants, Immunotoxicity and Immunotoxicity testing: An outline of in-vitro alternatives

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

New approaches to immunotoxicity testing.

New approaches to immunotoxicity testing are reviewed and discussed. A method of activating T-cells in vivo is presented which circumvents artifacts dur to viability effects encountered with in vitro mitogen assays. The use of adoptive transfer approaches to combine the advantages of in vitro manipulation with in vivo function assays is discussed relative to natural killer cells. The need for a...

متن کامل

CHEMICAL TESTING: Developmental Immunotoxicity in Review

Nanotechnology, the engineering of func­ tional materials at an atomic or molecular scale, has been among the fastest growing fields of science and technology. Worldwide sales of products incorporating nanotechnolo­ gy are projected to total $2.6 trillion by 2014, according to a 2004 report from Lux Research titled Sizing Nanotechnology’s Value Chain. But with the increasing use of nano materia...

متن کامل

Immunotoxicity of Asbestos

The study of asbestos immunotoxicity is generally applied toward understanding the mechanisms that lead to its infamous outcomes, mesothelioma and asbestosis, rather than as an outcome itself. However, emerging evidence suggests that asbestos exposure has critical inflammatory and autoimmune effects. Although crystalline silica is broadly accepted as an exposure trigger for systemic autoimmune ...

متن کامل

5 Immunotoxicity

As evidenced by recent documents prepared by the Office of Technology Assessment (9) and the National Research Council in 1992 (8) focusing on immunotoxicology, there has been growing interest and concern within the scientific and public communities on the capacity of environmental agents to perturb normal immune processes. The types of effects that may occur are often agent-specific as well as...

متن کامل

In vivo assessment of immunotoxicity

The organs, tissues, and cells of the lymphoreticular system have received considerable attention as targets for chemicals causing adverse effects. A basic toxicological approach is described for assessing the risk of a chemical perturbing the immune system. CD-1 mice were exposed for 14 or 90 days to one of several chlorinated hydrocarbons: 1,2-dichloroethane, 1,2-dichloroethylene or 1,1,2-tri...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Current Pharma Research

سال: 2011

ISSN: 2230-7834,2230-7842

DOI: 10.33786/jcpr.2011.v01i04.008