Improvement of Radioimmunotherapy Using Pretargeting

Improvement of Radioimmunotherapy Using Pretargeting

During the past two decades, considerable research has been devoted to radionuclide therapy using radiolabeled monoclonal antibodies and receptor binding agents. Conventional radioimmunotherapy (RIT) is now an established and important tool in the treatment of hematologic malignancies such as Non-Hodgkin lymphoma. For solid malignancies, the efficacy of RIT has not been as successful due to low...

A pretargeting system for tumor PET imaging and radioimmunotherapy

Labeled antibodies, as well as their fragments and antibody-derived recombinant constructs, have long been proposed as general vectors to target radionuclides to tumor lesions for imaging and therapy. They have indeed shown promise in both imaging and therapeutic applications, but they have not fulfilled the original expectations of achieving sufficient image contrast for tumor detection or suf...

Radioimmunotherapy of solid tumors: the promise of pretargeting strategies using bispecific antibodies and radiolabeled haptens.

234 The Impact of Lymphoscintigraphy Technique on the Outcome of Sentinel Node Biopsy in 1,313 Patients with Cutaneous Melanoma: An Italian Multicentric Study (SOLISM–IMI) Carlo Riccardo Rossi, Gian Luca De Salvo, Giuseppe Trifirò, Simone Mocellin, Giorgio Landi, Giuseppe Macripò, Paolo Carcoforo, Giuseppe Ricotti, Giuseppe Giudice, Franco Picciotto, Davide Donner, Franco Di Filippo, Maria Cris...

Pretargeting radioimmunotherapy of a murine model of adult T cell leukemia (ATL) with the alpha emitting radionuclide, Bi-213. Short Title: Pretargeting therapy of leukemia with Bi

the effect of using critical discourse analytical tools on the improvement of the learners level of critical thinking in reading comprehension

?it is of utmost priority for an experienced teacher to train the mind of the students, and enable them to think critically and correctly. the most important question here is that how to develop such a crucial ability? this study examines a new way to the development of critical thinking utilizing critical discourse analytical tools. to attain this goal, two classes of senior english la...