Improving the Breadth of the Host’s Immune Response to Lassa Virus
نویسندگان
چکیده
منابع مشابه
New Hosts of The Lassa Virus.
Lassa virus (LASV) causes a deadly haemorrhagic fever in humans, killing several thousand people in West Africa annually. For 40 years, the Natal multimammate rat, Mastomys natalensis, has been assumed to be the sole host of LASV. We found evidence that LASV is also hosted by other rodent species: the African wood mouse Hylomyscus pamfi in Nigeria, and the Guinea multimammate mouse Mastomys ery...
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15 صفحه اولTranscriptional Profiling of the Circulating Immune Response to Lassa Virus in an Aerosol Model of Exposure
Lassa virus (LASV) is a significant human pathogen that is endemic to several countries in West Africa. Infection with LASV leads to the development of hemorrhagic fever in a significant number of cases, and it is estimated that thousands die each year from the disease. Little is known about the complex immune mechanisms governing the response to LASV or the genetic determinants of susceptibili...
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ژورنال
عنوان ژورنال: Pathogens
سال: 2018
ISSN: 2076-0817
DOI: 10.3390/pathogens7040084