In Vitro Effects of SB202190 on Echinococcus granulosus
نویسندگان
چکیده
منابع مشابه
In Vitro Effects of SB202190 on Echinococcus granulosus
Spillage of cyst contents during surgical operation is the major cause of recurrence after hydatid cyst surgery. Instillation of a scolicidal agent into a hepatic hydatid cyst is the most commonly employed measure to prevent this complication. SB202190 is a pyridinyl imidazole derivative and is known to be a specific inhibitor of p38 MAPK. In the present study, the scolicidal effect of SB202190...
متن کاملEvaluation the scolicidal and cytotoxic effects of Froriepia subpinnataagainst protoscolex of Echinococcus granulosus in vitro
Background & Aim: Hydatidosis is one of the most important and prevalent parasitic diseases in Iran. Due to the fact that no definite and reliable treatment for this disease has been recorded so far, the aim of this study was to investigate the antiparasitic effect of Froriepia subpinnata (F. subpinnata) on the protoscolex stage of Echinococcus granulosus (E. granulosus) in vitro. Methods: F. ...
متن کاملIn vitro effects of nitazoxanide on Echinococcus granulosus protoscoleces and metacestodes.
OBJECTIVES Infection of humans and domestic ruminants with the larval stage (metacestode) of Echinococcus granulosus results in cystic echinococcosis (CE). The metacestode causes a space-occupying lesion in visceral organs, most commonly in the liver. Benzimidazole carbamate derivatives, such as mebendazole and albendazole, are currently used for chemotherapeutic treatment of CE. In human patie...
متن کاملIn Vitro Study of Nitric Oxide Metabolites Effects on Human Hydatid of Echinococcus granulosus
Hydatidosis is characterized by the long-term coexistence of larva Echinococcus granulosus and its host without effective rejection. Previous studies demonstrated nitric oxide (NO) production (in vivo and in vitro) during hydatidosis. In this study, we investigated the direct in vitro effects of NO species: nitrite (NO(2) (-)), nitrate (NO(3) (-)) and peroxynitrite (ONOO(-)) on protoscolices (P...
متن کاملEffects of X-ray on the metacestodes of Echinococcus granulosus in vitro
BACKGROUND Radiotherapy may represent an alternative treatment modality for cystic echinococcosis (CE), but there is no adequate evidence for it up to now. In this study, we aim to investigate the parasiticidal effects of X-ray on the metacestodes of Echinococcus granulosus in vitro. METHODS Protoscoleces obtained from sheep naturally infected with CE were cultivated in RPMI 1640 medium conta...
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ژورنال
عنوان ژورنال: The Korean Journal of Parasitology
سال: 2013
ISSN: 1738-0006
DOI: 10.3347/kjp.2013.51.2.255