In vitro evaluation of complement deposition and opsonophagocytic killing of Rhodococcus equi mediated by poly‐ N ‐acetyl glucosamine hyperimmune plasma compared to commercial plasma products
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چکیده
منابع مشابه
Development of Hyperimmune Equine Plasma to Virulence Associated Protein A (VapA) of Rhodococcus equi
Procedure – A proprietary formulation of ATCC 33701 Rhodococcus equi known to contain the virulence plasmid was developed and tested on 72 horses. Antibody levels to Rhodococcus equi Virulence associated protein A (VapA) were determined relative to a Standard Plasma. A clinical trial was performed on 28 foals. Seven foals were administered hyperimmune plasma and seven foals were administered pu...
متن کاملEffect of hyperimmune plasma on the severity of pneumonia caused by Rhodococcus equi in experimentally infected foals.
This study evaluated the prophylactic effectiveness of hyperimmune plasma (HIP) as an aid in the prevention of pneumonia caused by experimental infection with Rhodococcus equi. Thirty neonatal foals were administered R. equi HIP or saline at 2 days of age and were infected with virulent R. equi at 7 days. All foals developed signs or symptoms of respiratory disease. Radiographic scores on day 2...
متن کاملSurvival of foals with experimentally induced Rhodococcus equi infection given either hyperimmune plasma containing R. equi antibody or normal equine plasma.
The purpose of this study was to determine if colostrum-deprived foals with experimentally induced Rhodococcus equi pneumonia have a decreased severity of the disease and decreased mortality rate when given hyperimmune (HI) R. equi antibody plasma (R. equi titer at least 100 % and virulence-associated protein A [VapA] at least 10000) prophylactically versus when given normal equine plasma (R. e...
متن کاملMetabolomic Analysis of Blood Plasma after Oral Administration of N-acetyl-d-Glucosamine in Dogs
N-acetyl-d-glucosamine (GlcNAc) is a monosaccharide that polymerizes linearly through (1,4)-β-linkages. GlcNAc is the monomeric unit of the polymer chitin. GlcNAc is a basic component of hyaluronic acid and keratin sulfate found on the cell surface. The aim of this study was to examine amino acid metabolism after oral GlcNAc administration in dogs. Results showed that plasma levels of ectoine w...
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ژورنال
عنوان ژورنال: Journal of Veterinary Internal Medicine
سال: 2019
ISSN: 0891-6640,1939-1676
DOI: 10.1111/jvim.15511