In Vivo Imaging of Proteolytic Activity in Atherosclerosis
نویسندگان
چکیده
منابع مشابه
In vivo imaging of proteolytic activity in atherosclerosis.
BACKGROUND Atherosclerotic plaque rupture, the most important cause of acute cardiovascular incidents, has been strongly associated with vascular inflammation. On the basis of the hypothesis that the inflammatory response and proteolysis lead to plaque rupture, we have examined the role of cathepsin B as a model proteolytic enzyme. METHODS AND RESULTS Using western-type diet-fed apoE and apoE...
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ژورنال
عنوان ژورنال: Circulation
سال: 2002
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.0000017860.20619.23